How does interstitial cystitis develop




















Symptoms often worsen during menstruation. Common symptoms range from mild discomfort, pressure and tenderness to intense pain in the bladder and the surrounding pelvic area.

Diagnosing interstitial cystitis can be difficult, as there are a variety of symptoms associated with this condition. Many conditions and disorders must be ruled out before a diagnosis of IC can be considered, including the following:. Your physician has a number of diagnostic tools to help rule out other conditions and identify interstitial cystitis.

A urine sample is studied under a microscope to check for blood or bacteria in the urine which may indicate urinary tract infection, urinary tract stones or other problems.

Urine culture. A urine sample is studied to determine if there is any bacteria growing in it. The bacteria is then tested to determine which drugs will most effectively treat the bacteria. Urine cytology. An examination of the cells from the bladder lining that are in the urine. To check for prostatitis in men, prostatic fluid can be examined for signs of infection.

Cystoscopy with hydrodistention. This is the main diagnostic tool for interstitial cystitis. Since this procedure can be painful for someone with interstitial cystitis, it is usually performed while the patient is under general anesthesia.

The causes of interstitial cystitis are still unknown. Interstitial cystitis IC is a disorder in which the bladder the organ that stores urine before it is passed out of the body is overly sensitive, and usual causes for this, such as infection, cannot be found. The major symptoms are:. The pain can be in the area of the lower abdomen, urethra tube that carries urine from the bladder outside the body or vagina.

Sexual intercourse may be painful for women who have IC. The symptoms may range from just needing to urinate more often to severe pain and urgency. Work, sexual activity and normal social functioning can become difficult or impossible. The symptoms of IC may stay the same over time or get worse. Some patients may go into remission for extended periods. IC is most common in women, but it also occurs in men and children. An estimated , to 1 million Americans currently suffer from the disease.

The doctor must make sure that other diseases are not causing the symptoms. Similar symptoms may be caused by:. To make the diagnosis, your doctor usually begins with a general examination, including a pelvic exam and urinalysis. The urine is usually normal, with no signs of bacterial infection. For a definite diagnosis of IC, a cystoscopic examination is usually necessary. In this procedure, the patient is put under general anesthesia, the bladder is distended stretched with water and the doctor uses a telescopic device cystoscope to look inside the bladder.

The doctor may also take a biopsy a small sample of tissue from your bladder to help exclude other conditions. At this time, there is no cure for IC, nor is there one effective treatment that works for everyone. However, most IC patients are helped by one or more of the following treatments:. This type of treatment involves stretching the bladder by filling it with water under general anesthesia, as is done in the diagnosis of IC.

Certain medications are also used for this such as:. Eliminating certain foods, such as those that are acidic or spicy, may decrease the severity of IC symptoms. Also, cigarettes, coffee, tea and alcohol may irritate IC. These techniques can improve the quality of life and reduce the incidence and severity of flare-ups. Mayo Clinic does not endorse companies or products.

Advertising revenue supports our not-for-profit mission. This content does not have an English version. This content does not have an Arabic version. Overview Interstitial cystitis Open pop-up dialog box Close. Interstitial cystitis Your bladder, kidneys, ureters and urethra make up your urinary system. Request an Appointment at Mayo Clinic. Share on: Facebook Twitter. Accessed Sept.

Clemens JQ. Accessed July 1, Interstitial cystitis. Merck Manual Professional Version. Wein AJ, et al. Bladder pain syndrome interstitial cystitis and related isorders. In: Campbell-Walsh Urology. Philadelphia, Pa.



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