Marijuana Research Report How does marijuana produce its effects? People who have taken large doses of the drug may experience an acute psychosis, which includes hallucinations, delusions, and a loss of the sense of personal identity. Prev Next. July It may also, in the short-term, flood the brain with dopamine, the brain's reward signal, according to a study in the journal Nature.
Long-term, it may blunt dopamine's effects, the study found. That, in part, may explain some of the euphoria associated with a high, and places cannabis in the company of other drugs that people use to feel pleasure. The effects of a high from cannabis that's smoked or inhaled typically last for a few hours, though it can take edibles almost that long to start affecting users. And while cannabis isn't the dangerous substance it was made out to be in the 20th century , using it comes with some risk.
For one, while cannabis is legal for recreational and medical use in some states, it's still illegal in many parts of the country. It's also important to bear in mind that cannabis is a potent pharmacological substance. Cannabis can cross the placenta, so pregnant people should avoid it. And "heavy use in the teenage years can be problematic," Piomelli said.
For instance, cannabis — and especially synthetic cannabinoids like spice — can exacerbate psychosis. Finally, cannabis does affect the ability to drive, particularly in occasional users. Drew cautioned that people should not drive for three hours after smoking. Eventually, the THC will leave the brain; the profusion of blood that brought THC into the brain will carry it to the liver, where it will be destroyed and expelled in urine.
And you're not gonna believe this, but your hands — they were the same the whole time. Grant Currin is a freelance science journalist based in Nashville, Tennessee.
Cannabis smoke contains many of the same harmful chemicals found in cigarette smoke. Regularly smoking cannabis with tobacco increases the risk of a baby being born small or premature. Cannabis has not been linked to birth defects, but research suggests that using cannabis regularly during pregnancy could affect a baby's brain development as they get older.
Cannabis contains active ingredients called cannabinoids. This is used to relieve the pain of muscle spasms in multiple sclerosis. Another cannabinoid drug, called Nabilone, is sometimes used to relieve sickness in people having chemotherapy for cancer. Clinical trials are under way to test cannabis-based drugs for other conditions including cancer pain, the eye disease glaucoma , appetite loss in people with HIV or AIDS , and epilepsy in children.
Read the latest updates on cannabis, cannabinoids and cancer — the evidence so far on the Cancer Research UK website. Page last reviewed: 3 December Next review due: 3 December Cannabis: the facts - Healthy body Secondary navigation Body Bones Food for healthy bones Keep bones healthy over 65 Are you at risk of falling?
Foot problems and the podiatrist Looking after your feet with diabetes How to stop smelly feet. Lower your cholesterol Keeping your kidneys healthy Top 10 healthy heart tips. Keloid scars Dangers of black henna. Within minutes, your heart rate may increase by 20 to 50 beats per minute. That rapid heart rate can continue for up to 3 hours. This places extra oxygen demand on your heart.
If you have heart disease, this could raise your risk for a heart attack. One of the telltale signs of recent cannabis use is bloodshot eyes. The eyes look red because cannabis causes blood vessels to expand and fill with more blood. THC can also lower pressure in the eyes, which can ease symptoms of glaucoma for a few hours.
More research is needed to understand whether THC can offer long-term benefits for glaucoma. The effects of cannabis extend throughout the central nervous system CNS.
Cannabis is thought to ease pain and inflammation and help control spasms and seizures. Still, there are potential long-term negative effects on the CNS to consider. It may heighten your sensory perception and your perception of time. This dopamine cycle may also explain why as many as 30 percent of cannabis users develop cannabis use disorder. Severe cannabis use disorder, or addiction , may be relatively uncommon, but it can occur.
In the hippocampus , THC changes the way you process information, so your judgment may be impaired. Changes also take place in the cerebellum and basal ganglia.
These brain areas play roles in movement and balance. Cannabis may alter your balance, coordination, and reflex response. Very large doses of cannabis or high concentrations of THC can cause hallucinations or delusions. According to the NIDA , there may be an association between cannabis use and some mental health conditions like depression and anxiety.
You may want to avoid cannabis if you have schizophrenia or a family history of schizophrenia. Cannabis may make symptoms worse or increase the chances of developing the condition in people who have a genetic predisposition.
When you come down from the high, you may feel tired or a bit depressed. In some people, cannabis can cause anxiety.
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