How does accutane work chemically




















Accutane is the trade name for Isotretinoin. In some cases, health care professionals may use the trade name Accutane or other name cis-Retinoic Acid when referring to the generic drug name Isotretinoin. Drug type: Accutane is an anti-cancer chemotherapy drug.

This medication is classified as a retinoid. For more detail, see "How this drug works" section below. Note: If Accutane has been approved for one use, physicians sometimes elect to use Accutane for other problems if they believe it might be helpful.

Side effects of Accutane: Important things to remember about the side effects of accutane:. However, you should always inform your health care provider if you experience any unusual symptoms. When to contact your doctor or health care provider: Contact your health care provider immediately , day or night, if you should experience any of the following symptoms:.

The following symptoms require medical attention, but are not emergency situations. Contact your health care provider within 24 hours of noticing any of the following:.

Always inform your health care provider if you experience any unusual symptoms. If your blood is given to a pregnant woman, it may harm her unborn baby. Isotretinoin capsules can make you feel sleepy and dizzy. You also may not see as well at night. If this happens to you, do not drive, cycle, or use machinery or tools until you've stopped treatment. It's best to avoid alcohol while taking isotretinoin capsules, or at least keep the amount you drink to a minimum.

This is because there's a risk of damage to your liver - and that your cholesterol levels will increase. If you do drink, try not to drink more than the recommended guidelines of up to 14 units of alcohol a week. A standard glass of wine ml is 2 units. A pint of lager or beer is usually 2 to 3 units of alcohol. Page last reviewed: 18 January Next review due: 18 January Isotretinoin capsules Roaccutane On this page About isotretinoin capsules Key facts Who can and can't take isotretinoin capsules Side effects How to cope with side effects How and when to take it Advice for women Cautions with other medicines Common questions.

About isotretinoin capsules Isotretinoin capsules are a very effective treatment for severe acne spots. Isotretinoin capsules are also known by the brand names Roaccutane and Rizuderm. Isotretinoin capsules start to work after a week to 10 days.

They work very well - 4 out of 5 people who use them have clear skin after 4 months. You will a have blood test before you start taking isotretinoin and regular blood tests during your treatment. Your skin may become very dry and sensitive to sunlight during treatment. Using lip balm and moisturisers will help. It's very important not to become pregnant while using isotretinoin capsules and for at least 1 month after stopping.

This is because isotretinoin can harm an unborn baby. Women will be given a reminder card about this. If you become depressed or think about harming yourself while taking isotretinoin, stop taking the medicine and tell your doctor straight away. Isotretinoin capsules aren't suitable for some people.

Do not take isotretinoin capsules if you : have had an allergic reaction to isotretinoin, soya the capsules contain soya or any other medicines in the past have an inherited digestive disorder called fructose intolerance the capsules contain sorbitol To make sure isotretinoin capsules are safe for you, tell your doctor if you : have had a mental health illness like depression are pregnant or think you could be, or you're breastfeeding have ever had an allergic reaction to isotretinoin or any other medicine have liver or kidney disease have high levels of cholesterol or other fats in your blood have high levels of vitamin A have Crohn's disease or ulcerative colitis If you have diabetes , talk to your doctor before beginning treatment with isotretinoin capsules.

Common side effects The common side effects of isotretinoin capsules happen in more than 1 in 10 people. Talk to your doctor or pharmacist if these side effects bother you or don't go away: skin becoming more sensitive to sunlight dry eyes dry throat dry nose and nosebleeds headaches and general aches and pains Serious side effects Serious side effects are rare and happen in less than 1 in 1, people. Important Tell your doctor straight away if you become depressed or think about ending your life while taking isotretinoin capsules.

Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to isotretinoin capsules. Information: You can report any suspected side effect to the UK safety scheme. What to do about : dry skin or lips - apply a moisturiser and lip balm often the best type of moisturiser is an oil-free face moisturiser for sensitive skin.

Try to keep your showers shorter than 2 minutes, using lukewarm water rather than hot. Do not use a sunlamp or sunbeds. If you wear contact lenses and these become uncomfortable, you might have to wear glasses instead while you're taking this medicine. Light exercise shouldn't be a problem, but try to avoid heavy exercise as it may make joint or muscle pain worse.

It's important to take the capsules as instructed by your doctor. The dose of isotretinoin capsules varies from person to person, and depends on your weight. What if I forget to take it? Never take a double dose. Never take an extra dose to make up for a missed one. What if I take too much? Will the dose I take go up or down? This medicine is likely to harm a baby. It also increases the risk of miscarriage. Before starting treatment with isotretinoin capsules, women who are able to become pregnant must agree to: use at least 1, and ideally 2, reliable methods of contraception for 1 month before starting isotretinoin capsules, and for 1 month after treatment has stopped - the second contraceptive should be a barrier method of contraception for example, a condom , but you shouldn't use barrier methods on their own have a pregnancy test before, during, and 5 weeks after the end of treatment - some doctors may ask you to have monthly pregnancy tests Your doctor will give you a patient reminder card for isotretinoin.

Important Do not take isotretinoin capsules if you think you're pregnant, you know you're pregnant, or if you're breastfeeding. Accutane is the brand name for the medication isotretinoin. Like all retinoids, it is a derivative of Vitamin A. The brand Accutane is no longer available, but there are multiple generic forms of isotretinoin on the market. We at Minars Dermatology in Hollywood, FL see no significant difference between these brands and consider them interchangeable.

It is typically the second-line treatment for severe or cystic acne that has not responded to other oral or topical forms of treatment. Sometimes it is our first choice for patients who seem to be at risk for acne scars , or for patients who come to us after having failed other treatments.

Isotretinoin works by shrinking the oil glands in the skin that produce sebum. Sebum attracts bacteria that create acne. Women of child-bearing potential who take this drug must be on two forms of birth control or completely abstinent , as it can cause severe birth defects if taken while pregnant.

Most woman use 1- an oral contraceptive pill, and 2 — condoms as their two forms of birth control.



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